Does Mental Exhaustion Affect the Choices You Make?

Posted Posted in Jayne's blog

This scenario will feel familiar to many parents (or managers in the office….): Imagine spending the day watching your kids—making them breakfast, settling arguments, answering their questions and trying to keep them from getting bored. By the end of the day, you finally take a moment to think about what to make for dinner, and with it, whether you have the ingredients, how long it will take and whether your kids will even eat it. After an exhausting day, even simple tasks like making a meal can feel overwhelming.

That sensation is cognitive fatigue, and it can come up in all aspects of life. It’s the reason that an office worker performing boring computer tasks all day may feel too tired to go out with friends after work. And it’s also why a nurse who has just finished a long, demanding shift might opt against making one extra patient visit despite initial plans to check on someone.

Researchers, led by Vikram Chib at Johns Hopkins University and the Kennedy Krieger Institute, took a closer look at what happens in the brain when people are faced with decisions while mentally exhausted. This sense of cognitive fatigue isn’t just about feeling physically tired. The team demonstrated that it deeply impacts people’s decisions and willingness to exert effort. They found that repeated mental exertion can significantly decrease people’s motivation to engage in challenging tasks, and they pinpointed the areas of the brain that make this happen.

The scientists monitored brain activity in 28 people using functional magnetic resonance imaging (fMRI) while they first performed cognitively effortful tasks and then decided whether they were willing to exert more mental effort to earn some money. The monetary rewards allowed the researchers to put an exact dollar amount on people’s motivation at different states of fatigue.

While in the brain scanner, participants answered questions designed to test their working memory—a form of memory that allows people to hold multiple ideas in the brain at one time. Participants were asked to recall strings of letters, with varying degrees of difficulty. After the participants had been ‘warmed up’ and a bit worn out with these tasks, they were given a choice between an easy memory test with a $1 payout if they succeeded, or a harder memory test in which they’d earn up to $8 for answering correctly. As participants became more cognitively fatigued, they were much less likely to choose the more demanding option, even though it could pay more. This decision gave insight into understanding how cognitive fatigue can make people value possible rewards versus greater effort.

So what was happening in an exhausted brain that makes us behave differently? It turns out there’s a decision-making brain system that specifically takes levels of fatigue into account. As people completed ever-more-exhausting memory tasks, an area at the front of the brain called the dorsolateral prefrontal cortex sent out increasingly strong signals to the right anterior insula (pictured on the right), a region toward the middle-right of the brain that is known for monitoring how the body is feeling—including levels of fatigue. Based on the patterns the researchers were seeing, signals between these two brain areas were used to compute a person’s willingness to trade cognitive effort for reward. As people got more mentally exhausted, the activity between these two brain regions increased, meaning more and more signals were sent between the dorsolateral prefrontal cortex and right anterior insula. That greater connectivity between brain regions predicted a person being less inclined to take on the tougher memory task.

These findings can help us examine cognitive fatigue, both as it’s experienced in daily life and in certain conditions in which its effects are most pronounced, such as depression, long COVID and multiple sclerosis. (Much remains unknown about severe mental exhaustion).

Together, the brain systems that have been studied help determine whether a reward feels worth the effort. These fatigue signals have likely evolved to protect us from overtaxing our cognitive and physical systems. When fatigue signals are magnified, so, too, are the costs of exerting more energy.

But there are ways to push ourselves, even when we’re tired—and situations in which that extra push is worthwhile. Cognitive fatigue can often stop us from performing activities that might replenish our mental resources, such as taking a walk in the sunshine after work. And even after a long day at work or taking care of loved ones, there are still effortful but important tasks we may need to tackle, such as making healthy meal choices. Knowing the importance of an activity or finding it interesting can spur us past certain feelings of fatigue, research has shown. In other words, thinking about these activities in ways that reframe what you’re doing and why it matters can help you go that extra step.

REFERENCES:

Steward G, Looi V, Chib VS. The Neurobiology of Cognitive Fatigue and Its Influence on Effort-Based Choice. Journal of Neuroscience 11 June 2025, 45 (24) e1612242025; DOI: 10.1523/JNEUROSCI.1612-24.2025

Sutin AR, et al. A. Purpose in life and concurrent and incident fatigue. Psychol Health Med. 2025 Feb 21:1-11. doi: 10.1080/13548506.2025.2468105.

Milyavskaya M et al. More Effort, Less Fatigue: The Role of Interest in Increasing Effort and Reducing Mental Fatigue. Front Psychol. 2021 Nov 19;12:755858. doi: 10.3389/fpsyg.2021.755858.

 

Are Our Attention Spans Really Shrinking?

Posted Posted in Jayne's blog

Smartphones buzz, Internet tabs multiply and television episodes carry regular reminders to help people keep track of the plot. Surveys suggest that we feel less able to concentrate, teachers report distracted students and headlines declare that our attention spans are shrinking.

A century before social-media bans and advice to disable device notifications, the inventor and science-fiction writer Hugo Gernsback proposed a more extreme way to avoid distraction: an isolating wooden helmet (see photo above). Outside influences, he said, were “the greatest difficulty that the human mind has to contend with.” Gernsback’s isolator device — part diving suit, part monastic cell — did help him to work, he said, but it came with a risk of suffocation.

He later installed an air supply!😜😂

Concerns that sustained thought is under assault have become even more acute in the digital era. Research across psychology and neuroscience, however, has built up a more nuanced picture of what is happening to our attention spans. The results suggest that people do flit from one task to another more frequently than they did in previous decades, and that this switching is often detrimental to performance. But there is little evidence that the brain’s fundamental ability to concentrate has been impaired. This suggests that if we can shut down the distractions of our environment, it is possible to recover focus.

 

THE ATTENTION-SPAN CONFUSION

There’s a trend of people reporting that they feel like they can’t pay attention. They say they are constantly distracted, their attention jumps from one thing to another, and they can’t concentrate.

In a 2021 survey of more than 2,000 UK adults, almost half said they felt their attention span was shorter than it used to be. And two-thirds thought that the attention span of young people has declined. Teachers and schools around the world have responded to this perception with modular lessons that break topics into digestible pieces. Some students now study literary extracts rather than full novels. When the novelist Elif Shafak questioned why TED talks were becoming shorter, she said last year she was told that it was because “the world’s average attention span has shrunk.”

The idea of an average attention span carries intuitive appeal. But the way it’s discussed can tangle distinct concepts. Researchers distinguish between people’s capacity to pay attention, that is, their underlying ability to concentrate on a particular task, and their real-world behaviour, or what people actually focus on from moment to moment.

What’s more, the capacity to pay attention is the result of several processes in the brain. These include sustained attention, the ability to stay engaged with a task over time; selective attention, the ability to prioritise some information and ignore the rest; and executive control, the ability to steer attention in line with a goal rather than whatever happens to be more tempting.

 

ATTENTION IN THE LABORATORY

Capacity is measured under controlled laboratory conditions that test performance on a task — often a tedious one — over time. To test sustained attention, volunteers might monitor a screen showing streams of letters and shapes and identify specific changes. The ‘d2’ task, for instance, displays rows of letters, such as d and p, sometimes with dashes drawn above or below them, and asks people to mark the letter d only if it has two lines underneath.

Many lab studies have shown how performance on such tasks declines in about ten minutes, although the pattern of decline is not smooth: even apparently strong attention naturally fluctuates between bursts of good performance, lapses and recovery.

Further tests demonstrate how providing a distracting environment, such as playing sounds of babies crying and dogs barking, worsens people’s performance on cognitive tasks. This provides a basis for understanding distractions in the real world. Analyses have demonstrated that, for instance, traffic accidents are more likely to occur if drivers are talking on their phones.

The lab studies haven’t shown evidence that — when free of distractions — people’s underlying capacity to pay attention has changed. But there are differences in how people perform. Those who say they frequently juggle several streams of media at once tend to perform worse on tests of selective attention, for example showing greater difficulty filtering out irrelevant information. They also show differences in tests related to working memory and executive control.

But these correlations might only reflect that individuals with different attentional tendencies could be naturally drawn to switch focus more often; the observations can’t prove that their digital environment has causally altered their brains. And although attention deficit hyperactivity disorder (ADHD) diagnoses have increased in recent years, researchers generally attribute the rise to changes in awareness and access to assessment and diagnostic practice, rather than to an underlying change in people’s attention capacity.

Overall, there are no convincing data from controlled lab tests to support the idea that people have become less able to concentrate because the capacity of attention is being degraded over time. A 2024 meta-analysis of results from d2 tests performed by more than 21,000 people from 32 countries between 1990 and 2021 showed no differences in how children scored and, if anything, a slight improvement in adult performance.

It’s not so much that human biology has changed, it’s more a change in habits. And the question is how reversible those habits are.

 

REAL-WORLD MEASUREMENTS

The strongest evidence for change when it comes to attention is not from laboratory tasks but from measures of real-world behaviour. For two decades, Gloria Mark, a psychologist at the University of California, Irvine, has monitored how office workers use computers. Her studies, based on direct observation and digital tracking, show that the average duration of attention to a single task has steadily declined.

Mark’s work does not seek to measure sustained focus towards a specific goal. Instead, she counted when and how often workers switch between tasks. Such switches don’t have to be towards trivial distractions that would annoy the boss. They include opening a new browser tab, checking an email and moving between documents, as well as glancing at a phone. In the mid-2000s, she says, she observed that workers spent about two and a half minutes on average on a dedicated screen task before switching. By the 2010s, that was down to about 75 seconds, and in the early 2020s it was about 47 seconds, according to Mark’s 2023 book.

Often included in discussion of these results is a 2015 marketing report by Microsoft Canada, which stated that the average human attention span had fallen from 12 seconds in 2000 to 8 seconds in 2013. The report noted that this was shorter than a goldfish’s average attention span, which it reported as 9 seconds. But the report’s findings, based on surveys, filmed behaviour and electroencephalogram (EEG) data — which uses spikes in brain activity to measure when people switch their focus — reflected changing digital habits rather than cognitive limits and even noted that people were becoming more efficient at processing information. (Also, goldfish are unfairly maligned; there is no evidence that they have particularly short attention spans, and studies show they retain some information for months).

Mark’s research shows that frequent switching of attention carries a cognitive cost. When people switch, and especially when they switch fairly rapidly, which is what the data show, they tend to make more errors. It takes them longer to accomplish any single task compared with if they were to do work sequentially. And stress increases. Constant switching also diverts the kind of mental effort used. We’re not then utilising those skills of reflection, deliberation and working memory. This can lead to the familiar malaise of superficial busyness without seeming to make progress.

Every generation has a panic that new technology will undermine the ability to concentrate. But now we are in the digital age- and Mark does argue that it’s different: both the scale of information available and the speed with which we can access it has changed. Importantly, the nature of the competing pulls on our attention has changed, too. The modern environment does not simply impose distractions. It bombards us with alternatives that offer more immediate rewards. People are switching tasks so often and resetting their attention each time because they choose to do so, even if they don’t realize it.

If the alternatives are really rewarding and high value, then it will be very hard to focus on something else that’s going to require more subjective effort. That’s ‘high value’ as classed by a psychologist or neuroscientist — which is not necessarily the way a parent, teacher or your boss at work would see it. Notifications, messages and social-media feeds provide the brain with bursts of social validation, novelty and information.

Mark argues that these rewarding digital environments might be altering our attentional habits, including our tendency to drift even in the absence of obvious distraction. Her research suggests that the sources of interruptions are not solely external — such as the ping of an arriving message. And when external interruptions decrease, internal ones often increase — a pattern that suggests that distraction and switching can become habitual and leave attention more fragmented.

 

ARE OUR BRAINS ACTUALLY CHANGING?

Real-world studies such as Mark’s are too messy to generate reliable data on specific aspects of brain performance. But cognitive neuroscientist Nilli Lavie at University College London also worries that this constant switching could relate to weaker executive control. She suggests that it could have long-term implications for the brain.

Her work shows that the ability to control attention is linked to structural differences in the brain, specifically the amount of grey matter in regions of the frontal cortex. Using magnetic resonance imaging (MRI) scans and behavioural tests, she has shown that individuals with greater grey-matter volume in these areas perform better on tasks that require maintaining focus and resisting distraction. The grey-matter volume can be used to make accurate predictions about how people will perform, and might reflect a combination of genetic factors and long-term experience.

In principle, such measurements might be used to detect changes in attention capacity over time or between cohorts of people. Lavie doesn’t have the data to show that, and no such pattern has shown up in controlled lab studies, but she argues that it could happen. There is the possibility that you either exercise it and it’s got a good grey-matter volume, or you don’t, and it shrinks. A case of ‘Use it, or lose it’.

Monica Rosenberg (University of Chicago, Illinois) studies a different brain signature of attention. Using functional MRI, which measures brain activity, her team has identified patterns that link several systems, including the frontoparietal cortex, subcortical structures and the cerebellum, that together predict how well a person performs on sustained-attention tasks. These connectivity signatures are robust across individuals, populations and clinical groups, such as people with ADHD, and can be used to predict attention performance in people who haven’t been tested before.

Again, because patterns of connectivity can predict how well individuals perform on sustained-attention tasks, repeatedly scanning the same people could reveal whether that capacity is stable or changing. But Rosenberg’s studies so far are only snapshots or short-term, and focused on brain development rather than long-term changes.

 

HOW TO IMPROVE FOCUS

What does research on attention suggest about how we can improve our focus? Rosenberg thinks that if we want to change our attention, then changing our environments will be much more effective than changing ourselves.

One way is to remove known sources of external distraction, especially those that offer short-term value and reward, even if the distraction seems faint. In some studies of cognitive tasks, people do worse if they have their phone in their pocket, even if it’s on silent.

Because attention naturally switches to high-reward distractions, another strategy is to artificially inflate the value of the task at hand. Payments for accuracy and consistency on attention tasks reduce lapses, produce fewer errors and can slow the rate of attentional decline over time.

In a job and getting paid already? Feedback, internal competition and clear goals can help to make accuracy and consistency feel important. So can a sense that what you are doing matters.

If attention is shaped by habits, as Mark suggests, then it should also be possible to train and reverse those habits. Techniques such as mindfulness seem to strengthen the ability to notice when attention drifts and bring it back. Short breaks can restore performance.

And distraction itself is not always the enemy. An important finding from controlled lab studies of attention is that even when volunteers have no external distractions, their minds still wander, often without conscious awareness that they have gone off task.

Neuroscientist Michael Esterman at Boston University in Massachusetts, who has spent years studying these fluctuations, argues that the flickering of attention must originate in the brain as useful internal processes that can distract us, including thoughts, ruminations and worries. Periods of mind-wandering can support creativity, planning and problem-solving, enabling the brain to explore and integrate ideas.

Not only is sustained attention riddled with inevitable lapses, it is also shaped by mood, stress, sleep and anxiety, all of which influence both performance and how people interpret their own lapses. Negative moments loom large in memory, whereas successful concentration often passes unnoticed.

Most importantly, the steady performance on the lab studies suggests that despite the competing attractions of the modern world, focus can still be found when we really need it. We pay attention according to our goals. The question is what those goals have become.

And if nothing else works, there’s always a wooden helmet….

 

REFERENCES:

Arruda, A., Mesquita, C., Couto, R., Sousa, V. & Mendonça, C. Noise Health 25, 247–256 (2023).

Redelmeier, D. A. & Tibshirani, R. J. N. Engl. J. Med. 336, 453–458 (1997).

Ophir, E., Nass, C. & Wagner, A. D. Proc. Natl Acad. Sci. USA 106, 15583–15587 (2009).

Murphy, K. & Creux, O. Comput. Hum. Behav. 114, 106532 (2021).

Adam, D. Are attention spans really shrinking? What the science says. Nature 653, 20-22 (2026)

Andrzejewski, D., Zeilinger, E. L. & Pietschnig, J. Personalit. Individ. Differ. 216, 112417 (2024).

Mark, G. Attention Span (HarperCollins, 2023).

Eayrs, J. O. & Lavie, N. NeuroImage 202, 116148 (2019).

Rosenberg, M. D. et al. Proc. Natl Acad. Sci. USA 117, 3797–3807 (2020).

Ward, A. F., Duke, K., Gneezy, A. & Bos, M. W. JAssoc. Consum. Res. 2, 140–154 (2017).

Massar, S. A. A., Lim, J., Sasmita, K. & Chee, M. W. L. Biol. Psychol. 120, 21–27 (2016).

Esterman, M., Noonan, S. K., Rosenberg, M. & DeGutis, J. Cereb. Cortex 23, 2712–2723 (2013).

Longings and Longevity, Time and the Thymus

Posted Posted in Jayne's blog

 In energy healing sessions with clients, I regularly work with an area round the thymus called the Soul Seat. This is an area where, energetically, our longings sit. When we start to activate those, listen to them and work with them then our lives gain more meaning and direction. We feel happier and more fulfilled. And our health takes a turn for the better. Not unimportant.

When I came across this new research about the thymus and its link to longevity my healer’s brain sat up and took notice. If the thymus is linked to longevity and the thymus is linked to longings – then could it also be that following your longings leads to a longer life? It’s always tickled me (I love playing with words) that longings and longevity contain the same ‘long’ and that thymus sounds like time-us. But I digress….let’s get back to the research.

As far as organs go, the thymus is underrated. This little-known gland sits inside the chest next to the heart and the lungs. And while we typically retain it into adulthood, it is most active before and during puberty. At that time, the thymus is largely responsible for developing T cells, a critical type of white blood cell that help to fight infections. Its role in adults, however, has largely been overlooked for years, in part because it shrinks (and is replaced with fat tissue) as we age—a signal scientists had interpreted as meaning it was less relevant.

But now a pair of new studies suggest the organ may be far more important for our long-term well-being than we thought. The findings jibe with an emerging consensus that the immune system plays a major role in how well we age.

In one study published in March in the journal Nature, researchers used artificial intelligence to analyse around 27,000 patient computed tomography (CT) scans and medical records to reveal that the health of the thymus may be linked to whether an individual develops cardiovascular disease or lung cancer or dies from any cause.

Researchers believe that this finding is in an important puzzle piece for understanding long-term health. The AI analysis found enormous variation in the health of the thymus between individual people. In some people, it stayed very active until a very old age. And [in] other people, it actually declined very rapidly at a younger age.

Importantly, thymus health correlated with a person’s overall health. People who had a healthy thymus tended to live longer and were less likely to develop lung cancer or cardiovascular disease—even after accounting for factors such as what someone’s age or sex was and whether they smoked—than people with a less healthy thymus.

And in a related study also published in Nature in March, Hugo Aerts (researcher at Mass General Brigham and a professor at Harvard Medical School and Maastricht University in the Netherlands) and his colleagues found that, among cancer patients receiving immunotherapy, those who had a healthier thymus tended to have better treatment outcomes.

What these two studies show is that almost this forgotten organ, the thymus, may actually play a very central role in our health throughout life. 

Increasingly, different lines of research are converging on the idea that immune competence—particularly T-cell-mediated immunity—is a central determinant of healthy aging. Previous research has shown that patients who had their thymus removed experienced worse health outcomes years later, for example.

The research isn’t conclusive, however. The studies identify a correlation between the thymus and long-term health outcomes—but not a causal effect. It’s possible that the thymus could be acting as a proxy for overall physiological health rather than determining it.

Patients included in the new research who had better thymus health also tended to have lower inflammation. This could suggest that what is really being captured is a broader state of low inflammation and better global organ function rather than a thymus-specific effect. 

What remains compelling however is the message that a well-functioning immune system is likely one of the most impactful factors in maintaining health.

REFERENCES:

Bernatz, S., Prudente, V., Pai, S. et al. Thymic health consequences in adults. Nature 652, 986–994 (2026). https://doi.org/10.1038/s41586-026-10242-y

https://www.massgeneral.org/news/press-release/study-reveals-unexpected-importance-of-the-thymus-in-adults

Bernatz, S., Prudente, V., Pai, S. et al. Thymic health and immunotherapy outcomes in patients with cancer. Nature 652, 995–1003 (2026). https://doi.org/10.1038/s41586-026-10243-x

Kooshesh, K.A et al. Health Consequences of Thymus Removal in Adults. N Engl J Med, 389 (5), 406-417. https://www.nejm.org/doi/full/10.1056/NEJMoa2302892

How a ‘Face-Swapping’ Illusion Can Unlock Childhood Memories

Posted Posted in Jayne's blog

As we get older, one of the quiet frustrations is how early memories begin to blur. The vivid details of the never-ending summer holidays or the magical white Christmases can fade and melt like the ice-cream on that summer day…That leaves us wondering whether there’s a way to somehow bring them back.

Scientists call these recollections of personal life events autobiographical episodic memories—the mental time‑travel that lets us re‑experience what we once saw, heard, tasted, touched, smelled, and felt. But memories aren’t just about the world around us; they’re also tied to the bodies we inhabited at the time. With every moment, the brain receives a constant stream of sensory signals from the body. In theory, our memories should encode not only what happened but who we physically were when it happened. Surprisingly, this connection has barely been studied.

A team of neuroscientists lead by Jane Aspell, wondered whether tapping into this brain‑body link could help people access long‑lost memories—by briefly putting them “back inside” their younger selves. In a new experiment, they found that altering someone’s sense of their own body can unlock memories from specific periods of life. A subtle illusion—showing people a childlike version of their own face that moved exactly as they did, like a mirror—made early memories more vivid.

The brain constantly tracks the body, building internal maps of its shape, position, and state. This mental model, known as the bodily self, was once thought to be stable. But research shows it’s surprisingly flexible. When the brain receives conflicting sensory information, it can be tricked into updating its sense of the body. Classic illusions, like the rubber hand illusion (see references), show how easily ownership can shift. Virtual reality takes this further, allowing people to feel as though they inhabit an entirely different body. The enfacement illusion can even make another face feel like one’s own.

These illusions reveal that our bodily self is not fixed—it can be reshaped, at least temporarily, by changing what the brain perceives.

In the study, the researchers used this malleability to make people feel younger. Fifty adults took part in an online experiment where they saw a real‑time video of their face. Half saw their unaltered appearance; the other half saw a younger, childlike version created with an image filter. When participants moved their heads and saw the younger face move in perfect sync, many felt a strong sense of ownership over that younger version.

Afterward, participants recalled childhood and recent memories in detail. Independent raters, unaware of which condition each person experienced, scored the vividness of these recollections. People who saw the younger face retrieved significantly richer childhood memories—more sensory details, more emotion, more specificity. The effect didn’t extend to recent memories, suggesting the illusion taps into a deep link between body representation and memories formed long ago.

These findings suggest that the brain doesn’t store memories as isolated sensory fragments. Instead, it anchors them to the body we had when those memories were formed. The bodily self isn’t just background—it’s part of the structure of memory itself.

Beyond being a fascinating trick, this work hints at new possibilities. If early memories are tied to how we once perceived our bodies, then carefully designed illusions or sensory interventions might one day help people who struggle to access their past—such as those with dementia or brain injuries.

Memories aren’t simple data points. They’re woven from sensations, emotions, and the shifting sense of who we were at different stages of life. By reconnecting with the bodies of our past, we may reopen doors to the memories that shaped us. To me, as a therapist and healer, this could open up a door in the future to help people heal from trauma in an inventive therapeutic way.

REFERENCES:

Robyn Fivush. 2011. The Development of Autobiographical Memory. Annual Review Psychology. 62:559-582. https://doi.org/10.1146/annurev.psych.121208.131702

Gupta, U., Bright, P., Clarke, A. et al. Illusory ownership of one’s younger face facilitates access to childhood episodic autobiographical memories. Sci Rep 15, 32564 (2025). https://doi.org/10.1038/s41598-025-17963-6

Legrand, D. The Bodily Self: The Sensori-Motor Roots of Pre-Reflective Self-Consciousness. Phenom Cogn Sci 5, 89–118 (2006). https://doi.org/10.1007/s11097-005-9015-6

Botvinick, M., Cohen, J. Rubber hands ‘feel’ touch that eyes see. Nature 391, 756 (1998). https://doi.org/10.1038/35784

Pyasik, M., Ciorli T., & Pia L. Full body illusion and cognition: A systematic review of the literature. Neuroscience & Biobehavioral Reviews, 143, 104926 (2022). https://doi.org/10.1016/j.neubiorev.2022.104926.

Do Skin Cells Remember Inflammation for Life?

Posted Posted in Jayne's blog

Skin remembers.

That scar on your chin from when you fell off your bike aged 7.

That freckle from the summer you turned 13.

Our skin is an archive of moments from our lives, and now scientists have found it really does remember. For people with inflammatory skin conditions such as psoriasis, the skin’s memory manifests in flare-ups in the same spots over and over. And now scientists think they know precisely why this happens.

In a new study in mice published less than a week ago in Science, researchers showed how skin cells inherit patterns of gene expression every time they regenerate. The team found not only that successive generations of skin cells maintain the memory of their DNA’s structure but also that the cells inherit chemical modifications to the DNA called epigenetic marks, which can turn on or off, or turn certain genes up and down in a process called gene expression.

Scientists knew that stem cells had the ability to change their behaviour and remember, but they didn’t know if it was through this epigenetic mechanism. What this current paper does is definitively demonstrate that it’s through marking of DNA that it allows that stem cell to now behave differently moving forward.

Skin stem cell memory can be beneficial: if you get a cut, for example, your skin will heal faster in that place if it is injured again because the cells remember the experience. But that becomes problematic in conditions like psoriasis, for which the memory of a flare-up can make the tissue overly sensitive to environmental triggers such as stress, leading to chronic inflammation.

Researchers now realise that our DNA can remember a past injury far longer than was thought that it could. For the study, an artificial intelligence model was used to help identify specific genetic sequences in mice that drive skin stem cell memory over the long term. They did this by asking the model to look at how regions of the cells’ DNA behaved at different time points before and after an injury—in this case, a ‘punch biopsy’, which involved making a very small incision on the mice’s back (ouch!). The AI findings were like “opening a black box” that the researchers then further verified.

And while mice are not humans, the biology the team has identified is highly conserved across animals.  This suggests the finding may have some applicability to humans.

The new research opens the door to testing it in humans. But these studies will be more difficult because, whereas mouse skin cells regenerate on timescales of days and chronic disease is measured in months or perhaps one to two years, human skin cells do so on the order of several weeks or months, and chronic disease can be lifelong.

What is increasingly clear from the evidence is that inflammation can change the trajectory of the body’s biology. The researchers are now starting to ask questions along the lines of ‘If we could reverse that experience/memory – and thus reverse the damage – you could really improve people’s health.’

I love it when science catches up! Welcome to healing and self-development :=)

REFERENCES:

Christopher J. Cowley et al. Distinctive DNA sequence features define epigenetic longevity of inflammatory memory. Science Vol. 391, issue 6792 (2026). DOI:10.1126/science.adz6830

Naik, E et al. Inflammatory memory sensitizes skin epithelial stem cells to tissue damage. Nature550, 475–480 (2017).

Naik, E. Fuchs, Inflammatory memory and tissue adaptation in sickness and in health. Nature 607, 249–255 (2022).

R. Holt, S. J. Kirk, M. C. Regan, M. Hurson, W. J. Lindblad, A. Barbul, Effect of age on wound healing in healthy human beings. Surgery112, 293–297 (1992).

You’re Not Crazy! Pain Really Does Linger Longer in Women

Posted Posted in Jayne's blog

Pain is universal, but it isn’t equal. Some people recover quickly after an injury, while others experience lingering discomfort that seems to outstay its welcome. For decades, scientists assumed these differences were mostly psychological or hormonal. But new research is revealing a far more intricate story — one in which the immune system, not just the nervous system, plays a starring role.

A 2026 study by Jaewon Sim and colleagues has uncovered a biological mechanism that helps explain why pain duration differs between males and females. Their work doesn’t just deepen our understanding of pain; it opens a window into how our bodies heal, how stress affects recovery, and why personalised wellbeing strategies matter more than ever.

When we think of pain, we picture nerves firing, not immune cells circulating. Yet the immune system is deeply involved in how pain begins, intensifies, and eventually fades.

Sim and colleagues focused on monocytes, a type of white blood cell that rushes to sites of injury or inflammation. These cells release a cocktail of chemical signals — some that amplify pain, and others that help resolve it.

One molecule in particular stood out: interleukin‑10 (IL‑10).

IL‑10 is often described as an “anti‑inflammatory peacekeeper.” It calms overactive immune responses and helps tissues return to balance. But the study revealed something more nuanced: IL‑10 doesn’t behave the same way in males and females, and this difference shapes how long pain persists.

The researchers discovered that male and female monocytes produce IL‑10 differently, and this leads to distinct pain trajectories:

  • In one sex, IL‑10 is released in a way that efficiently resolves inflammation, shortening the duration of pain.
  • In the other, IL‑10 production is less effective or differently timed, allowing pain signals to linger.

This isn’t about one sex being “better” at healing than the other — it’s about different immune strategies, shaped by evolution, hormones, and cellular communication patterns.

The takeaway is profound: Pain duration isn’t just psychological or hormonal — it’s immunological.

Understanding the immune system’s role in pain opens up new ways to think about self‑care, resilience, and recovery.

  1. Your Body’s Stress Response Shapes Pain

Stress hormones influence immune cells, including monocytes. Chronic stress can disrupt IL‑10 production, making it harder for the body to “switch off” pain.

This means practices that regulate stress — mindfulness, sleep hygiene, breathwork, social connection — aren’t just feel‑good add‑ons. They’re biological tools that help your immune system resolve pain more effectively.

  1. Men and Women May Need Different Recovery Strategies

Because IL‑10 behaves differently across sexes, the most effective pain‑management approaches may differ too. This doesn’t mean one-size-fits-all advice is useless — but it does mean personalised wellbeing is the future.

  1. Inflammation Is a Whole‑Body Experience

Pain isn’t isolated to the site of injury. It’s a systemic conversation between immune cells, nerves, and the brain. Supporting your immune system through nutrition, movement, and rest can meaningfully influence how long pain sticks around.

The study by Sim et al. is part of a growing movement in science: understanding health not as a set of isolated systems, but as an interconnected network.

Pain, immunity, stress, and wellbeing are not separate chapters — they’re one story.

This research suggests that future therapies might:

  • Target monocytes directly
  • Boost or modulate IL‑10 production
  • Tailor treatments based on sex‑specific immune responses

But you don’t need futuristic medicine to benefit from these insights today. Simply recognising that your immune system plays a role in pain can shift how you approach recovery.

If you’ve ever wondered why your pain lasts longer than someone else’s, or why recovery feels unpredictable, this research offers a compassionate reminder:

Your body isn’t failing you — it’s following its own biological script.

And that script is shaped by:

  • Your immune system
  • Your stress levels
  • Your environment
  • Your sex-specific biology
  • Your lifestyle habits

Understanding these factors empowers you to work with your body rather than against it.

Pain is not just a signal; it’s a story your body is telling about healing, protection, and balance. The discovery that monocyte‑derived IL‑10 drives sex differences in pain duration adds a new chapter to that story — one that blends cutting‑edge immunology with practical insights for everyday wellbeing.

Science is showing us that healing is not linear, not identical across individuals, and not purely neurological. It is a dynamic dance between the immune system and the nervous system, influenced by biology, stress, and environment.

And that means the path to feeling better is both deeply personal and deeply biological — a reminder that self‑development and self‑care are not luxuries, but essential partners in the science of healing.

REFERENCE:

Jaewon Sim et al., Monocyte-derived IL-10 drives sex differences in pain duration. Sci. Immunol.  (2026) 11, eadx0292. DOI:10.1126/sciimmunol.adx0292

Can Reiki Really Deliver Rapid Relief? New Research Says Yes!

Posted Posted in Jayne's blog

Reiki has long occupied a curious space between personal healing practice and emerging scientific interest. While often categorised as a complementary or energy‑based therapy, its growing presence in hospitals, community centres, and wellness programs suggests something more than a passing trend. A recent exploratory study conducted across high‑stress communities in Chicago offers a compelling look at how even brief Reiki sessions may influence stress and pain—two of the most pervasive challenges in modern life.

 

Why Study Reiki Now?

A 2024 American Psychiatric Association poll found that 43% of adults felt more anxious than the previous year, citing political tension, economic instability, and gun violence as major contributors. High‑stress professions—such as police,ambulance peronal, educators, and community violence intervention workers—face even greater burdens. These groups often underutilise traditional mental‑health services due to stigma, accessibility issues, or fear of professional repercussions.

Reiki, a Japanese practice developed in 1922 by Mikao Usui, involves light touch or hands‑off energy work intended to support the body’s natural healing response. While its mechanisms remain debated, clinical research has increasingly documented reductions in anxiety, pain, fatigue, and stress across diverse populations. Hospitals—including many top American institutions—now incorporate Reiki programs, reporting benefits for patients undergoing surgery, cancer treatment, or palliative care.

Yet one question remains underexplored: Can very short, community‑based Reiki sessions—outside hospital settings—meaningfully reduce stress and pain?

 

Inside the Chicago Study

Between 2022 and 2024, volunteer practitioners offered ten‑minute Reiki sessions at 59 events across Chicago. Settings ranged from police academies and fire stations to college campuses, homeless veteran fairs, community violence intervention organisations, and juvenile detention centers. The environments varied dramatically—from quiet rooms with soft lighting to bustling outdoor fairs with DJs and food stalls.

A total of 1,724 participants received Reiki. Before and after each session, they rated their stress and pain on a 1–10 scale using simple emoji‑based visuals. Afterward, they also shared open‑ended feedback about how they felt.

No demographic data was collected, and the study did not include a control group—appropriate for an exploratory design focused on perceived experience rather than causal claims.

What Happened After 10 Minutes?

The results were striking:

  • Stress decreased by an average of 72.6%.
  • Pain decreased by an average of 63.3%.
  • All reductions were statistically significant (p < 0.01).

These changes were consistent across all six community groups studied—first responders, trainees, veterans, academic communities, at‑risk neighborhoods, and individuals connected to the correctional system.

What People Said

A word‑frequency analysis of qualitative feedback revealed the most common responses:

  • Deep relaxation
  • Emotional release
  • Reduced physical discomfort
  • A sense of “lightness” or “something lifted”
  • Gratitude and surprise

Many participants expressed surprise—sometimes profound—at how different they felt after such a short session. Some described a sense of “lightness,” emotional release, or the feeling that “something was removed.” Others referenced spiritual or religious experiences, though Reiki itself is not affiliated with any religion.

Interestingly, the ambience of the setting—calm vs. chaotic—did not significantly alter outcomes. Even in loud, crowded environments, participants reported substantial relief.

Why Might Reiki Help?

While the study did not investigate mechanisms, prior research offers clues:

  • Stress and pain are deeply intertwined; chronic stress increases pain sensitivity, and chronic pain increases anxiety and depression.
  • Reiki has been associated with reductions in sympathetic nervous system activation (the “fight‑or‑flight” response).
  • Touch‑based or presence‑based therapies may enhance parasympathetic activity, promoting relaxation and pain modulation.

The Chicago findings align with a large body of clinical research showing Reiki’s potential benefits for anxiety, pain, fatigue, sleep, and quality of life.

 

What This Study Adds

Most Reiki research involves long sessions (30–90 minutes) in clinical settings. This study shows that:

  • Even 10 minutes can make a measurable difference.
  • Non‑clinical, community‑based delivery is feasible and impactful.
  • Large‑scale volunteer programs can reach populations underserved by traditional mental‑health systems.

The study’s scale—over 1,700 participants—makes it one of the largest of its kind.

Limitations and Future Directions

As an exploratory study, it cannot establish causality. There was no control group, no demographic data, and qualitative analysis was descriptive rather than thematic. Still, the consistency and magnitude of the results suggest that brief Reiki sessions warrant more rigorous investigation.

Future research could explore:

  • Controlled trials comparing Reiki to placebo or other relaxation techniques
  • Longitudinal effects of repeated short sessions
  • Physiological measures (heart rate variability, cortisol)
  • Structured qualitative interviews for deeper insight

 

Why This Matters

In a world where stress is rising and access to mental‑health care remains uneven, low‑cost, low‑risk, community‑based interventions are invaluable. Reiki—simple to learn, gentle to receive, and adaptable to many environments—may offer a scalable tool for supporting well‑being in high‑stress populations.

The Chicago study doesn’t claim Reiki is a cure‑all. But it does suggest that even a brief moment of intentional, compassionate presence can shift someone’s internal state in meaningful ways. And that, in itself, is worth paying attention to.

REFERENCE:

McCutcheon and S.K Habiya (2025). Investigating perceived stress and pain reduction following brief Reiki sessions in high-stress communities: an exploratory study.Frontiers in Psychology,  Volume 16. DOI=10.3389/fpsyg.2025.1625414

Should We Chase the Good—or Worry Less About the Bad?

Posted Posted in Jayne's blog

For decades, Cognitive Behavioural Therapy (CBT) has been considered the gold standard for treating depression and anxiety—conditions that will affect around one in five people during their lifetime. CBT has strong evidence behind it and, for many, it reduces distressing symptoms such as low mood, fear, and catastrophic thinking.

Yet there is a growing recognition within scientific circles that CBT does not work for everyone. Research shows that only about half of patients benefit, and only half of those experience lasting improvement. Crucially, while CBT often helps reduce negative emotions, it does not reliably restore positive ones—such as happiness, excitement, or a sense of aliveness.

Psychologists had always assumed that by reducing negative emotions—anger, fear, anxiety, sadness—the natural consequence would be for positive emotions to rise on their own. But…they don’t.. not reliably.

This insight has prompted a quiet but profound shift in therapeutic thinking.

Turning Therapy on Its Head

Rather than focusing primarily on correcting distorted thoughts or dampening distress, researchers like Michelle Craske at the University of California, Los Angeles are exploring therapies that actively cultivate positive emotional states—even when those states are fleeting, subtle, or initially uncomfortable.

These approaches borrow tools from CBT but reorient the goal: not merely reducing suffering, butstrengthening the nervous system’s capacity for pleasure, connection, and reward. Large-scale clinical trials in the U.S. and U.K. suggest this shift may be especially powerful for people who experience anhedonia—the blunting or loss of positive emotion that often accompanies depression and anxiety.

One of the most researched of these approaches is Positive Affect Treatment (PAT), developed by Craske and Alicia Meuret of Southern Methodist University. PAT has now been tested in multiple National Institutes of Health–funded trials, comparing it with a CBT-style approach called Negative Affect Treatment (NAT).

Participants in these studies all lived with depression and/or anxiety, and many struggled to feel pleasure at all. Results showed that PAT was significantly more effective than NAT for people with moderate to severe symptoms and pronounced anhedonia.

Reawakening the Brain’s Reward System

PAT is grounded in decades of research showing that people who struggle to feel pleasure are more vulnerable to anxiety and depression. Brain imaging studies reveal that, in many of these individuals, neural circuits involved in reward processing are underactive.

Craske and her colleagues focused on strengthening this system through three key stages of reward:

  • Anticipation (wanting)
  • Consumption (enjoying)
  • Learning (remembering and integrating)

In simple terms: learning to look forward to, fully experience, and mentally store positive moments.

Imagine a teenage girl who hears Taylor Swift is coming to town and eagerly offers to clean the house for a month if her parents buy tickets. That’s anticipation. At the concert, she feels euphoric—that’s enjoyment. Later, she realises the cheaper seats were still great, making future concerts feel more accessible. That’s learning.

For someone with depression or anxiety, any one of these steps may be blocked.

From Correcting Thoughts to Savoring Experience

Consider a woman who tells her therapist she used to love having lunch with a friend, but now feels numb during the meal and worse afterward. After a recent lunch, she spirals into self-criticism—convinced she was boring, that her friend left early because of her, and that she’ll eventually be alone.

In traditional CBT, therapy would focus on challenging these beliefs, examining evidence, and calming the body’s fear response.

In PAT, the therapist takes a different route.

The woman is gently asked to identify anything enjoyable about the lunch—however small. Perhaps the aroma of food made her hungry. Perhaps her friend laughed at a story. Perhaps there was a warm hug at the end. She is then guided to linger with these moments, sensing them fully and imagining their return.

This deliberate savouring—combined with practices such as gratitude and generosity—helps retrain the brain to register and retain positive experiences, much like energy healing practices that attune awareness to subtle but life-giving sensations.

Beyond Positivity: A Practical Balance

Another emerging approach, Augmented Depression Therapy (ADepT), overlaps with PAT but goes further. Developed by Barney Dunn at the University of Exeter in England, ADepT works pragmatically with both positive and negative emotions.

Rather than asking whether a thought is “true” (as CBT does), ADepT asks whether it is useful. If someone about to give a talk feels like an imposter, CBT might challenge the belief. ADepT might instead offer a stabilising alternative: “I know enough about this topic, and I will do an okay job.”

Clinical trials show that ADepT outperforms CBT not only in reducing symptoms, but in improving overall well-being. Eighty percent of participants improved, compared with sixty percent in CBT—and more importantly, they were more likely to stay well a year later.

This translates into: choosing to turn toward the positive helps get more people better, and helps them to stay better for longer.

Why Happiness Can Feel Unsafe

One challenge with positivity-focused therapies is that many people are deeply afraid of happiness. Some believe joy is fleeting and will be followed by disaster. Others feel undeserving. Many unconsciously suppress pleasure because it feels unfamiliar or unsafe. People with depression often employ a whole set of behaviours to snuff out the joy because it feels uncomfortable.

Anxiety adds another layer. Many anxious individuals believe that worrying protects them—that expecting the worst prevents emotional devastation. This phenomenon, known as contrast avoidance, causes people to dampen joy before it can fully arise.

To address this, researchers have developed tools like SkillJoy, an experimental phone app created by Lucas LaFreniere and Michelle Newman. The app encourages users to notice and remain with positive feelings—even when discomfort arises. Early trials show it significantly reduces contrast avoidance.

A New Gold Standard?

Other “positive therapies” are emerging, including amplification of positivity treatment (designed to improve social connection) and behavioural activation therapy, which has long been used to treat anhedonia.

Rather than replacing CBT, these approaches may become part of a hybrid future—one that recognises that some people need first to calm fear, while others long most deeply to feel joy, meaning, and vitality again.

As Craske notes, therapy should be tailored. Someone overwhelmed by panic may benefit most from CBT. Someone who feels empty, flat, or disconnected may need help turning gently toward pleasure. For patients, capturing these moments and building on them can be transformative.

As the year closes and a new one opens, perhaps healing is not only about releasing what hurts—but about learning, patiently and courageously, to let the good in.

REFERENCES

Craske, M. G. et  al. (2023). Positive affect treatment targets reward sensitivity: A randomized controlled trial. Journal of Consulting and Clinical Psychology, 91(6), 350–366. https://doi.org/10.1037/ccp0000805

Dunn, Barnaby D. et al. (2023) Preliminary clinical and cost effectiveness of augmented depression therapy versus cognitive behavioural therapy for the treatment of anhedonic depression (ADepT): a single-centre, open-label, parallel-group, pilot, randomised, controlled trial. eClinicalMedicine, Volume 61, 102084. DOI: 10.1016/j.eclinm.2023.102084

LaFreniere LS, Newman MG  (2023). Reducing contrast avoidance in GAD by savoring positive emotions: Outcome and mediation in a randomized controlled trial. J Anxiety Disord. Jan;93:102659.doi: 10.1016/j.janxdis.2022.102659

Taylor, C. T. et al (2024). Amplification of Positivity Treatment for Anxiety and Depression: A Randomized Experimental Therapeutics Trial Targeting Social Reward Sensitivity to Enhance Social Connectedness. Biological Psychiatry,Volume 95, Issue 5, Pages 434-443. https://doi.org/10.1016/j.biopsych.2023.07.024

Cernasov, P. M. et al. (2024). A parallel-arm, randomized trial of Behavioral Activation Therapy for anhedonia versus mindfulness-based cognitive therapy for adults with anhedonia. Behaviour Research and Therapy, Volume 182, 104620. https://doi.org/10.1016/j.brat.2024.104620

Craske, M.G. et al. Positive affect and reward processing in the treatment of depression, anxiety and trauma. Nat Rev Psychol 3, 665–685 (2024). https://doi.org/10.1038/s44159-024-00355-4

Do Childhood Relationships Affect Your Adult Attachment Style?

Posted Posted in Jayne's blog

In therapy, healing and trauma work it’s long been known that our earliest relationships affect our later ones. We come into the world screaming and vulnerable—entirely dependent on adult caregivers to keep us safe and teach us how to connect with others. The nature of these earliest relationships influences how we behave towards others and see the world long after we’ve grown—but in more complex and nuanced ways than researchers previously thought, according to the results of a large, decades-long study examining how the quality of children’s interactions with parents and close peers went on to influence their relationships in adulthood.

In particular, early dynamics with mothers predicted future attachment styles for all the primary relationships in participants’ lives, including with their parents, best friends and romantic partners, the study found. It was found that people who felt closer to their mothers and had less conflict with their mothers in childhood tended to feel more secure in all of their relationships in adulthood. This is s a really striking finding because it demonstrates the enduring impact of that first person who is supposed to be there for you.

Early childhood friends also played a strong role in predicting how participants approached their future close friendships—and their romantic connections. Those first friendships at school help us practice give-and-take dynamics. Relationships in adulthood then mirror those dynamics.

The idea that earliest relationships have an outsized impact on our lives was popularized in psychology by Sigmund Freud. British psychiatrist John Bowlby later incorporated some core Freudian elements to create attachment theory, which helps explain variations in how people approach close relationships. Some people are quite comfortable depending on others, opening up to them and using them as a secure base, whereas other people lack that confidence and trust.

Researchers today define attachment styles by where people fall along two dimensions, each shaped by early experiences with caregivers. The first, attachment anxiety, measures your level of confidence in the availability and responsiveness of those you are close to. People high in attachment anxiety might have more intense fears of abandonment or need for reassurance. The second factor, attachment avoidance, involves how comfortable you feel opening up to others and depending on them for support. Those high in avoidance may believe that people cannot be counted on or trusted, so they avoid asking for help or emotional support—even if they need it. A relationship with high attachment anxiety, avoidance or both is defined as more insecure, while a relationship that is low in both attachment anxiety and avoidance is considered to be secure: You feel comfortable and close to the other person, you trust them to be there for you, and you feel supported.

It can be difficult to study exactly how early relationships go on to influence attachment style, though, because people’s retrospective reports of what happened to them in childhood are skewed by memory failings and emotional and cognitive biases. Of the relatively few studies that have examined associations between early caregiving experiences and adult attachment styles, she adds, all have focused almost exclusively on a single early relationship: the maternal one.

To more deeply understand how early relationships with a wider variety of people impact attachment styles, researchers Dugan, Fraley and their colleagues turned to a landmark longitudinal study of 1,364 children and their families from around the U.S. It began when the children were infants and ended when they were 15 years old. Once the young participants were old enough to speak, they were surveyed about the quality of their relationships with their fathers, mothers and best friends. Researchers also surveyed participants’ primary caregivers—who were mostly their mothers—and observed them interacting with their children. That study showed robust evidence that early experiences with caregivers matter for social development.

Between 2018 and 2022, 705 of the original participants, who by then were 26 to 31 years old, agreed to a follow-up study to collect information about their current relationships with their parents, best friends and romantic partners. For those 705 participants, Dugan and her colleagues analysed associations between the quality of early relationships and later attachment styles in adulthood. They found several notable patterns. First, a person’s relationship with their mother tended to set the stage for their later attachment style in general, as well as for their specific approaches to individual relationships with friends, romantic partners and fathers. For instance, people who had more conflict with their mothers, were less close to their mothers or had mothers who were reportedly harsher and showed less warmth during childhood and adolescence tended to feel more insecure in their adult relationships.

The researchers didn’t find many associations between participants’ relationships with their fathers and their future attachment styles—perhaps because most identified their mother as their primary caregiver. This cohort’s first assessment was in 1991, and even though the burden of caregiving still heavily falls on mothers, fathers were even less involved back then, on average. In cases where a father was the primary caregiver, the results might be flipped—but that data was not collected.

Early experiences with close friends, though, were an even stronger predicter than maternal relationships for determining participants’ approach to—specifically—romantic relationships and friendships in adulthood. In general, if you had high-quality friendships and felt connected to your friends in childhood, then you felt more secure in romantic relationships and friendships at age 30. People who enjoyed increasingly close and deepening friendships across childhood and adolescence also showed significant gains in those departments as adults.

The study’s decades-spanning data are uniquely valuable and allowed the authors to show, using sophisticated analyses, how early social experiences affect later adult personality and close interpersonal relationships.  There has been much praise for the new study because it is seen as exceptionally rigorous and methodologically sound. The scientists have been able to provide some of the strongest prospective evidence to date supporting a foundational assumption of attachment theory: that early relational experiences shape how adults relate to others—not just in general but also within specific types of relationships.

Since the participants were still in early adulthood in the most recent analysis, future work could examine whether the same early-life factors continue to be so influential throughout life—and how major life transitions, such as parenthood, bereavement or divorce, might reshape those dynamics. Single-parent families, multigenerational households and same-sex couples could also be studied in future research. Participants in the current study were nearly 80 percent white, so more racial and ethnic diversity is needed to get a truly representative sample.

Dugan also emphasises that the findings do not mean the past inexorably dictates the tone of a person’s relationships in adulthood. You are definitely not doomed! Evidence supports that adult attachment styles can change in response to later life events and can even fluctuate month to month in response to both positive and negative relationship experiences. These findings show attachment styles are malleable. So relax…you can have a not-so-great relationship with your parents and still develop a secure and healthy bond with a close friend or romantic partner in adulthood.

REFERENCES:

Dugan, K. A. et al (2025). A prospective longitudinal study of the associations between childhood and adolescent interpersonal experiences and adult attachment orientations. Journal of Personality and Social Psychology. https://doi.org/10.1037/pspi0000502

Love, S. (2023). Love and the Brain: Do Partnerships Really Make Us Happy? Here’s What the Science Says. https://www.scientificamerican.com/podcast/episode/love-and-the-brain-do-partnerships-really-make-us-happy-heres-what-the-science-says/

Fraley, R. C. et al. (2015). Are adult attachment styles categorical or dimensional? A taxometric analysis of general and relationship-specific attachment orientations. J Pers Soc Psychol. Aug;109(2):354-68. Epub 2015 Jan 5. PMID: 25559192. https://doi: 10.1037/pspp0000027

Brennan, K. A., Clark, C. L., & Shaver, P. R. (1998). Self-report measurement of adult attachment: An integrative overview. In J. A. Simpson & W. S. Rholes (Eds.), Attachment theory and close relationships (pp. 46–76). The Guilford Press.

Fraley, R. C., Waller, N. G., & Brennan, K. A. (2000). An item response theory analysis of self-report measures of adult attachment. Journal of Personality and Social Psychology, 78(2), 350–365. https://doi.org/10.1037/0022-3514.78.2.350

The NICHD Study of Early Child Care and Youth Development (SECCYD). https://www.nichd.nih.gov/sites/default/files/publications/pubs/documents/seccyd_06.pdf

Fraley, R. C. et al. (2021). Do life events lead to enduring changes in adult attachment styles? A naturalistic longitudinal investigation. J Pers Soc Psychol. Jun;120(6):1567-1606. Epub 2020 Aug 13. PMID: 32790474. https://doi: 10.1037/pspi0000326

Dugan, K. A. et al. (2025). Genetic and environmental contributions to adult attachment styles: Evidence from the Minnesota Twin Registry. Journal of Personality and Social Psychology, 128(3), 639–669. https://doi.org/10.1037/pspp0000516

Can Small, Easy Acts of Joy Lead to Big Gains in Happiness?

Posted Posted in Jayne's blog

There is no shortage of programs or practices that promise to increase happiness. People may meditate for 30 minutes every morning, block off full evenings to deeply connect with close friends or commit to a 12-week daily gratitude journaling exercise. Some of these activities, which emerged from the field of positive psychology, can reliably and sustainably boost psychological well-being, a technical term for happiness in life. But let’s be honest. Most people feel too busy, tired or overwhelmed to add on—and then keep up with—new and demanding routines in day-to-day life.

What if finding more happiness did not require a major time commitment or lifestyle overhaul? What if, instead, it could come from simple, brief actions such as texting a genuine “thank you” to a colleague, asking a friend to share something that made them feel proud, looking at the sky’s vastness with wonder, or marveling at the intricate details of a wildflower?

A group of scientists set out to explore this question by investigating whether brief daily activities, or “micro acts,” can affect overall happiness in life. They also investigated how doing happiness-promoting micro acts might ripple outward in ways that enhance mutual care, compassion, and generosity.

This research began as a spin-off from a film called Mission: Joy—Finding Happiness in Troubled Times (see https://missionjoy.org)  in which the 14th Dalai Lama and the late archbishop Desmond Tutu talked about their friendship and offered lessons on creating joy for oneself and others regardless of circumstances. The film’s producer and co-director Peggy Callahan and impact producer Jolene Smith teamed up with psychologists Elissa Epel and Emiliana Simon-Thomas to develop a meaningful way for people to act on the film’s messages.

The result was a free, globally available online resource called the Big Joy Project (see Freebie section below) carrried out from the University of California, Berkeley. People who signed up for this project received a daily email or text that included a link to instructions for a five- to 10-minute micro act, defined as a short, simple activity for building joy. The opening micro act, for example, invited participants to listen to a 42-second audio clip of different people laughing, including the Dalai Lama and Desmond Tutu. It’s a simple, uplifting moment designed to elicit a smile or chuckle. The rest of the activities are delivered each day for seven days and included making a gratitude list, doing something kind, reflecting on a core value, feeling loving kindness (or a state of tenderness and consideration to others), reframing a difficult experience, celebrating another person’s joy, and watching an awe-inspiring video.

People who joined the project also answered several questions along the way. On a scale from “not at all” to “a lot,” they rated how positively and how negatively they felt before starting and after completing each micro act. People could also reflect on their experience doing each micro act in writing both just afterward and during an evening check-in. Most people reported that they found the micro acts easy and appealing to do. Since its launch, more than 112,000 people across more than 215 countries or territories have joined the Big Joy Project and have done more than 450,000 micro acts. These numbers make it the largest-ever community science project on joy in the world.

The research team gradually expanded with collaborators at several institutions, and together the analysed the data. In two recently published articles, the scientists reported that the micro acts add up in meaningful ways. They compared people’s responses to 18 questions presented before starting the Big Joy Project with most of those questions presented again at the end of seven days. Analysing responses from 17,598 people from 169 countries and territories, they found that people reported higher emotional well-being, more positive emotions, lower stress, and even modest improvements in sleep quality and physical health.

It took surprisingly little time and effort for people to feel better. Although many well-being programs span eight weeks or more, the Big Joy project yielded meaningful changes after just one week. And the more of the micro acts people completed, the more their happiness improved.

Importantly, the benefits weren’t limited to those who had more privilege or access to resources and opportunities. People who reported greater levels of social disadvantage, such as increased financial strain, lower educational attainment and lower subjective social status, often noted greater boosts to well-being as well.

The Big Joy Project also increased people’s self-reported prosociality—that is, their innate impulse to help others and connect with communities. People said they felt more inclined to reach out, offer support and attend to the needs of people around them after completing the project. Once again, there was a clear “dose-response” relationship: the more micro acts a person did, the greater their improvement in prosocial tendencies was.

The biggest increases in this impulse were observed among the least expected groups. Men, whose prosociality scores were lower before beginning the project, showed the largest improvement after seven days. Increases were also more pronounced among people who rated themselves lower in socioeconomic status and for those living in Global South countries. These results suggest happiness-promoting micro acts can have a more pronounced effect where they may be needed most.

In a world grappling with loneliness, burnout and ideological division, small reminders of inspiration, kindness and connection can be powerful. When people experience more joy in their lives, they also tend to be more generous with their time and resources. And when people want to give more to one another, everyone benefits.

Certainly, there is still more for scientists to investigate. For example, the work relies on people reporting their own progress and feelings. It would also be interesting to run the study again but with a subgroup of “control” participants who do not complete daily micro acts. However, for the time being, the current  studies do make a compelling case for how modest steps can have remarkable benefits.

Why do such small actions work? The researchers think it’s because they activate the same psychological ingredients as longer, more involved programs: they boost positive emotions, inspire feelings of connection and help people feel more aligned with what brings them meaning and purpose. Indeed, many of these behaviours—practicing gratitude and being more sociable, for instance—have been well studied for years and found to be beneficial to the doer or giver. But the Big Joy Project is special in its simplicity. It’s low key. People who participated in Big Joy also developed a stronger sense of agency—a feeling that they can control their happiness and that they don’t have to wait for good things to happen to feel happy.

Perhaps that’s what makes the project so powerful. People mired in busyness wait impatiently for a promotion, holiday, new car/house/handbag or entertaining event, expecting to finally feel good. But this project teaches a different lesson. Simple, daily micro acts can ratchet up happiness in a more empowering way. Deliberately finding gratitude, offering kindness or giving ourselves moments to experience awe are not passive acts. They are courageous and effective ways of gently steering your own ship, even through stormy times.

REFERENCES:

D. Folk & E. Dunn. How Can People Become Happier? A Systematic Review of Preregistered Experiments.Annu. Rev. Psychol. 2024. 75:467–93. https://doi.org/10.1146/annurev-psych-022423-030818

D. Guevarra et al. Scaling a Brief Digital Well-Being Intervention (the Big Joy Project) and Sociodemographic Moderators: Single-Group Pre-Post Study. J Med Internet Res 2025, 27:e72053. https://doi.org/10.2196/72053

H. Goel et al. Promoting Prosociality via Micro-acts of Joy: A Large-Scale Well-Being Intervention Study. Proceedings of the 2025 CHI Conference on Human Factors in Computing Systems (CHI ’25).Article 721, 1–28. https://doi.org/10.1145/3706598.3713947

Are Mondays Really More Stressful on the Brain and Body?

Posted Posted in Jayne's blog

For decades the term “Monday blues” has been shorthand for the collective groan that greets the start of each workweek. It’s also well documented in medical statistics. Mondays come with higher rates of anxiety,stress and even suicide compared with other days. Studies on the phenomenon across whole countries have found a 19 percent increase in the odds of sudden cardiac death from confirmed heart attacks and other cardiovascular events on Mondays, affecting men and women across age groups.

It now turns out that the effect of Mondays can extend well beyond fleeting fluctuations in mood. Researcher Tarani Chandola at the University of Hong Kong recently discovered that people who report feeling anxious on Mondays show evidence of heightened activity in the body’s stress-response system over months. More surprisingly, this effect persisted among older adults who were no longer in the workforce, suggesting that, for some people, the stress of Mondays is a lifelong burden.

The biological underpinnings of the “Monday effect” have long been unclear, however. Is the stress and anxiety experienced on Monday biologically distinct? And could this be leaving a mark on people’s body even after they stop working?

To answer these questions, Chandola focused on the stress hormone cortisol. The hypothalamus-pituitary-adrenal (HPA) axis, a central stress pathway linking brain and body, manages much of people’s response to stress. When we experience a stressor—whether it’s something psychological, such as a looming deadline, or physical distress, such as a biting cold morning—the brain triggers the release of cortisol. The hormone helps us to manage short-term stress by mobilising energy and sharpening focus. But chronically high levels of cortisol disrupt the brain and bodily systems, increasing the risk of anxiety, depression, cardiovascular disease, diabetes, and obesity and impairing immune function.

Previous research had shown that cortisol levels can be higher on weekdays than weekends, but few studies had directly examined whether Mondays are uniquely stressful at a biological level. To investigate further, Chandola turned to the English Longitudinal Study of Aging (ELSA), which follows more than 10,000 adults aged 50 and older in England.

Chandola focused on a subset of these participants, asking them questions including, “Overall, how anxious did you feel yesterday?” People also reported which day of the week “yesterday” was. To assess the long-term biological toll of stressful days, the study analysed cortisol levels in participants’ hair samples in order to measure cumulative cortisol production over the past two to three months.

Of the 3,511 participants, 281 people reported feeling anxious on a Monday and 1,080 on another day of the week. Some of these volunteers also provided a hair sample, which let Chandola analyse how hair cortisol levels compared between groups. Crucially, the study also considered whether participants were still working or retired to see if the Monday effect was tied to the all-too-real demands of starting the workweek.

The results were striking. Older adults who reported feeling anxious on Mondays had, on average, 23 percent higher levels of cortisol in their hair samples collected up to two months later, compared with those who felt anxious on other days. This association was strongest among those with the highest cortisol levels—a group at particular risk for health problems associated with chronic stress.

In contrast, anxiety reported on other days of the week did not predict higher cortisol levels. And the effect was not limited to those still working; retirees who felt anxious on Mondays also showed elevated cortisol. In other words, the biological impact of Monday anxiety appears to persist even after the regimen of the workweek fades from daily life.

Some of the reason people show elevated cortisol on Mondays is that they feel more anxious on those days than others. But that’s not the whole explanation. The data show that the effect of anxiety on cortisol is magnified on Mondays. In other words, feeling anxious on the first day of the workweek has a much larger effect on the body’s stress hormones than feeling anxious on other days.

Why might Mondays, in particular, exert a powerful effect on the body? One possibility is that the transition from the weekend to the structured demands of the week is inherently stressful, and some people adapt to it better than others. Another is that Mondays present a higher level of uncertainty. Previous research from Becker  has indicated that anticipation and uncertainty represent key drivers of stress and anxiety. For those who don’t adapt to the weekly cycle, the repeated stress of Mondays may accumulate over the course of a lifetime, eventually leading to long-term problems in the body’s ability to regulate the stress system, which in turn can increase the risk of disease.

It is also possible that some people become anxious on Mondays so routinely that it becomes an automatic bodily response, one that persists even when the original trigger (such as a stressful job) is gone. This effect could reflect deeply ingrained habits of mind and body, shaped by decades of routine.

The recent findings indicate that, for some people, Monday blues are not a personal minor inconvenience but a persistent stressor with long-term—perhaps lifelong—detrimental effects on physical and mental health. The increased risk of heart attacks and other health events on Mondays is unlikely to be a random coincidence. Hospitals and clinics may need to plan for a surge in events at the start of the week, especially among older adults.

In addition, interventions aimed at helping people adapt to the start of the week might have long-term health benefits. The brain’s stress response is plastic, meaning that it can change. Practices that support emotion regulation, including meditation, mindfulness, regular physical activity or good sleep hygiene may help recondition the brain’s weekly cycle and attenuate stress-related health risks.

Finally, researchers will need to investigate why some people are resilient to Monday anxiety while others are not. That question could guide future studies and mental health strategies, opening the door to interventions that help people start the week not just with a groan but with greater resilience.

Also, with the shift in our working lives – following Covid – when many now work from home on a Monday, I wonder what that effect will have. Since companies often now ask their workers to be present on Tuesdays and Thursdays, will we in 20 years time have more stress associated with Tuesdays than Mondays? Now there’s food for thought.

REFERENCES:

Areni, C. S. et al. (2011). Factors Affecting the Extent of Monday Blues: Evidence from a Meta-Analysis. Psychological Reports, 109(3), 723-733. https://doi.org/10.2466/13.20.PR0.109.6.723-733

Eunkyong, K. et al (2098). Blue Monday Is Real for Suicide: A Case–Control Study of 188,601 Suicides. Suicide and Life-Threatening Behavior Volume 49 (2), 393-400. https://doi.org/10.1111/sltb.12429

Witte, D. et al. (2005). A Meta-analysis of excess cardiac mortality on Monday. Eur J Epidemiol Volume 20, 401–406. https://doi.org/10.1007/s10654-004-8783-6

Chandola, T. et al (2025). Are anxious Mondays associated with HPA-axis dysregulation? A longitudinal study of older adults in England. Journal of Affective Disorders, Volume 389, 119611.  https://doi.org/10.1016/j.jad.2025.119611.

Kunz-Ebrecht, S.R. et al. (2004). Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohort. Psychoneuroendocrinology. Volume 29(4), 516-28. https://doi/10.1016/s0306-4530(03)00072-6

Liu X, et al. (2024). A neural signature for the subjective experience of threat anticipation under uncertainty. Nat Commun. Feb 20;15(1):1544. https://doi/10.1038/s41467-024-45433-6

Creswell, D. J. Learning to Accept Discomfort Could Help You Thrive. Scientific American, 10 November 2023. https://www.scientificamerican.com/article/learning-to-accept-discomfort-could-help-you-thrive/

Young, L. J. Science-Backed Sleep Tips from 2024 to Help You Snooze Better. Scientific American, 13 December 2024. https://www.scientificamerican.com/article/science-backed-sleep-tips-from-2024-to-help-you-snooze-better/

Around the Globe With Self-Care

Posted Posted in Jayne's blog

You’ve heard of armchair travel, right?

Well this is armchair travel with a twist. Cultures from around the world have cultivated well-being in many fascinating ways—and science agrees that they’re effective! Better yet? They won’t cost you a thing.

Self-care goes global!

  1. Spanish siesta

Let’s start with a bit of winter warmth. In Spain and other Mediterranean places, as well as Latin America and some places in Asia, it’s common practice to take an after-lunch nap, called a “siesta” in Spanish. This afternoon nap time is not just for kids—adults do it too! It’s taken so seriously that museums, shops, and churches usually close for a couple of hours, and everything shuts down.

Adult nap time isn’t just a nice treat to indulge in. Researchers have found that, among generally healthy Greeks, those who partake in regular napping had a 37% lower chance of dying from heart disease within a few years of enrolling in the study. So if you have the ability to take a short nap during the day, try it out! As long as it doesn’t mess up your nighttime sleep, it may be a great way to get an extra boost of well-being.

 

  1. Danish “hygge”

I love the cold. I love coming in after a walk feeling like an ice cube and then being welcomed (and defrosted) by my warm kitchen. And I love being able to curl up with a book on long winter nights. I  love hot baths.

But I know that there are many who definitely don’t share my love of freezing weather!

In 2016, Denmark ranked as the happiest nation in the world in the World Happiness Report. Then, Finland became number one for the next three years, with Norway and Sweden never far behind. Did you ever wonder at the fact that the five happiest countries in the world are almost always cold, Nordic countries. How do they do it?

Of course, there are likely many factors involved. These countries often have less income inequality, greater oil wealth, and breathtaking natural landscapes. But I wondered if there were any specific Nordic secrets to happiness and wellness—even during winter.

The Danish believe in hygge (pronounced “hoo-gah”), which loosely translates to “coziness” and sounds to me a lot like ‘hug’! The word originated from an Old Norwegian word meaning “well-being,” and it captures all that is cozy, warm, and enjoyable. Curling up under a soft blanket while holding a warm mug of cocoa is hygge. Chatting with friends and family around a fire is hygge. And simply enjoying the glow of a candle is hygge.

This concept of hygge not only gives practical inspiration for how to enjoy life—oversized scarves and hot drinks —but it also offers a philosophy for how to be with one’s environment instead of fighting against it. No wonder the Danes are happy in winter!

  1. Japanese forest bathing

On the subject of being with the environment, we’ll ‘travel’ now eastwards to Japan, to take a dip in the woods. Not an actual swim, but rather, an immersion in nature called “shinrin-yoku,” loosely translated to “forest bathing.”

Forest bathing is exactly what it sounds like—being immersed in nature. Importantly, it’s not about going camping, hiking, or doing any hardcore exercise in a forest. In fact, it’s not a goal-oriented activity at all. It’s simply being with nature, with your senses open and your body as your guide.

Health researcher Dr. Qing Li and his colleagues have found that forest bathing enhances the immune system and encourages the expression of anti-cancer proteins. They also found that it decreases depression, fatigue, anxiety, and unsurprisingly, heart rate.

To take a forest bath yourself, you don’t need to seek out special destinations. You can simply find a spot of nature, even if it’s just a group of trees or a garden, and walk through the area slowly and aimlessly. Turn off your mobile phone and simply let the forest in through your five senses.

 

  1. Indian laughter yoga

Who doesn’t enjoy a good belly laugh? But have you ever done it on purpose? The idea of (Indian) laughter yoga is that we don’t have to wait for something funny to happen in order to laugh. Instead, laughter can and should be practiced for its own sake.

Laughter yoga is often practiced in groups, where real playfulness and interaction between people can turn practiced laughs into real guffaws. And there seem to be real health benefits, even if the laughter is “fake.”

A recent meta-analysis found that simulated laughter may be even more effective than spontaneous, humorous laughter for improving mood. So why not give it a try—do a belly laugh like no one is watching. Or better yet, get together with others and laugh with them!

  1. South African Ubuntu philosophy

Speaking of being with others, perhaps nothing captures our social human nature better than the South African philosophy of Ubuntu. This term from the Zulu language can be translated as “humanity towards others,” and it’s part of a phrase that means “a person is a person through other people.” This idea has been spread, in part, by Archbishop Desmond Tutu, a South African theologian, and human rights activist.

The word Ubuntu can be translated as ‘humanity towards others,’ and is part of a phrase that means ‘a person is a person through other people.’

Ubuntu is different from the other items here because it’s not just a practice, but rather, a whole humanist philosophy that embraces diversity, compassion, warmth, and dignity for all.

This may be a philosophy we especially need right now, even if living by it might be a lifelong pursuit. We can begin by acknowledging the humanity of all people, being open to learning, and respecting all, even if we’re unfamiliar or in conflict with someone.

  1. Jewish Sabbath

Observing the Sabbath, the seventh day of the week, is a religious tradition in the practice of Judaism. The Shabbat—meaning “rest” or “cessation”—begins on Friday evening and ends on Saturday evening, during which people refrain from work. Instead, they honour the Sabbath with restful activities like meditation, contemplation, and having festive meals with family. This is what Christian cultures traditionally also do (or did) on  the Sunday – the day of rest.

Research has found that Sabbath-keeping is beneficial for physical and mental health. One Jewish writer, Menachem Kaiser, has referred to the Sabbath as “the only authentic form of leisure: the act and fulfillment of doing absolutely nothing productive” and “our best bet to enact lasting communities.” This sounds like a much-needed balm for our modern hurts.

Research has found that Sabbath-keeping is beneficial for physical and mental health. This is unsurprising, given that much research has established the benefits of rest, spirituality, and even simply eating meals together as a family. So even if you’re not religious, you can practice a secular version of Shabbat and let this weekly time out give you the chance to rest and connect with others. And if you manage to turn off your mobile phone for a day too then you’re really doing well!

Whether it’s through the quietness of forest bathing, or the exuberance of laughter yoga, so many wellness practices and philosophies from around the world get back to the basics—feeling connected to our bodies, our minds, and one another. None of the ideas require you to buy a single thing. All of them invite us to be mindful and connected. And that would be my Christmas and New Years wish for this year!

REFERENCES:

* Naska A, Oikonomou E, Trichopoulou A, Psaltopoulou T, Trichopoulos D. Siesta in Healthy Adults and Coronary Mortality in the General Population. Arch Intern Med. 2007, 167(3):296–301. doi:10.1001/archinte.167.3.296

*World Happiness Report. https://worldhappiness.report

* Li, Q et al. Forest bathing enhances human natural killer activity and expression of anti-cancer proteins. Int J Immunopathol Pharmacol, Apr-Jun 2007; 20(2 Suppl 2): pages 3-8.

* Li, Q et al. Effects of Forest Bathing on Cardiovascular and Metabolic Parameters in Middle-Aged Males. Evid Based Complement Alternat Med. 2016; 2016: 2587381

* Li, Q. Forest Bathing Is Great for Your Health. Here’s How To Do It. https://time.com/5259602/japanese-forest-bathing/

See also Dr Li’s book ‘Forest Bathing: How Trees Can Help You Find Health and Happiness’. Viking (Penguin Publishing Group), 2018.

* van der Wal, N.C and Kok, R.N. Laughter-inducing therapies: Systematic review and meta-analysis. Social Science & Medicine Volume 232, July 2019, Pages 473-488.

* Superville, D. J., Pargament, K. I., & Lee, J. W. (2014). Sabbath Keeping and Its Relationships to Health and Well-Being: A Mediational Analysis. The International Journal for the Psychology of Religion24(3), 241–256. https://doi.org/10.1080/10508619.2013.837655

* S. M. Fruh et al. The Surprising Benefits of the Family Meal. The Journal for Nurse Practitioners, Volume 7, Issue 1, 2011, Pages 18-22, https://doi.org/10.1016/j.nurpra.2010.04.017